Case Series


Postpartum severe hyponatremia in preterm birth and mature newborns: Dangers for mother and child?

,  ,  ,  ,  

1 Department of Obstetrics and Gynecology, Center for Ultrasound and Prenatal Medicine, Buergerhospital and Clementine Children’s Hospital, Frankfurt am Main, Germany

2 Department of Neonatology and Pediatric Intensive Care, Buergerhospital and Clementine Children’s Hospital, Frankfurt am Main, Germany

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Felix Sierra

Department of Obstetrics and Gynecology, Center for Ultrasound and Prenatal Medicine, Buergerhospital and Clementine Children’s Hospital, Frankfurt am Main,

Germany

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Article ID: 100074Z08FS2021

doi: 10.5348/100074Z08FS2021CS

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How to cite this article

Sierra F, Kunzmann S, Mouzakiti N, Sabarai N, Bahlmann F. Postpartum severe hyponatremia in preterm birth and mature newborns: Dangers for mother and child? J Case Rep Images Obstet Gynecol 2021;7: 100074Z08FS2021.

ABSTRACT


Introduction: Sodium is the ion with the highest extracellular concentration and thus also determines the osmolality in the extracellular space. The lower the serum sodium, the more serious the dilemma.

Case Series:

Case 1: A eutrophic female was born at 37+3 weeks gestation, birth by vacuum extraction, birth weight 2570-gram, umbilical cord blood gas analysis performed in delivery showed severe hyponatremia (sodium 122 mmol/L).

Case 2: A eutrophic male was born at 40+4 weeks gestation, spontaneous labor, birth weight 3230-gram, suspicion of cerebral seizure, postpartum hyponatremia, perinatal metabolic acidosis, respiratory failure, and hypoxic ischemic encephalopathy.

Case 3: A eutrophic male was born at 38+4 weeks gestation, spontaneous birth, birth weight 2895-gram, postpartum severe hyponatremia, suspicion of cerebral seizure, cyanosis attacks.

Case 4: A preterm female was born at 31+1 weeks gestation, birth weight 1195-gram, sodium 125 mmol/L, potassium 6.3 mmol/L with respiratory disorder.

Conclusion: We recommend a quick diagnosis and stop the factors that cause hyponatremia. Laboratory tests, history, and physical examination could reduce hyponatremia to ensure adequate treatment.

Keywords: Fetal hyponatremia, Laboratory tests include serum sodium, Maternal hyponatremia, Plasma osmolality, Urine sodium and osmolality

SUPPORTING INFORMATION


Acknowledgments

I thank Dr. Volker Behrens for the professional English critical revision for the manuscript.

Author Contributions

Felix Sierra - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Steffen Kunzmann - Acquisition of data, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published

Niki Mouzakiti - Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published

Nafisa Sabarai - Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published

Franz Bahlmann - Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2021 Felix Sierra et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.