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Case Report
Recurrent placental chorioangioma in the setting of Fontan circulation: A case report
1 Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, OH, USA
2 Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA
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Mahmoud Abdelwahab
MD, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, 410 W. 10th Ave, Columbus, OH 43210,
USA
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Article ID: 100099Z08MA2021
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How to cite this article
Abdelwahab M, Cleary EM, Parkinson B, Cackovic M, Rood KM. Recurrent placental chorioangioma in the setting of Fontan circulation: A case report. J Case Rep Images Obstet Gynecol 2021;7:100099Z08MA2021.ABSTRACT
Introduction: The incidence of cardiac disease in pregnancy continues to increase, particularly pregnancy with complex congenital heart diseases. Fontan circulation is a unique circulation surgically created for individuals with single ventricle physiology, effects of which on developing placenta and fetus are not completely understood. Chronic placental hypoxia in Fontan circulation might explain increased incidence of chorioangioma in those patients.
Case Report: We present the case of a 28-year-old female with congenital pulmonary atresia and an extracardiac Fontan circulation with fenestrations and chronic right to left shunting, with baseline oxygen saturation of 87–91%. She had three successful pregnancies. Placentomegaly has been noted in all her pregnancies, with recurrent chorioangioma noted in her first and last pregnancy.
Conclusion: Fontan circulation with chronic hypoxia may be associated with increased risk of giant chorioangioma with potential for adverse perinatal outcomes. Ultrasound screening for large chorioangioma therefore may be beneficial in this subset of patients.
Keywords: Chorioangioma, Congenital heart disease in pregnancy, Fontan circulation in pregnancy, Placentomegaly
SUPPORTING INFORMATION
Author Contributions
Mahmoud Abdelwahab - Substantial contributions to conception and design, Drafting the article, Final approval of the version to be published
Erin M Cleary - Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Bryce Parkinson - Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Michael Cackovic - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Kara M Rood - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2021 Mahmoud Abdelwahab et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
