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Case Series
Amniotic band syndrome: A case series
1 DO, CPT, MC, US Army, PGY4, Brooke Army Medical Center, Obstetrics & Gynecology, San Antonio, Texas, USA
2 MD, Col, USAF, Brooke Army Medical Center, Chief of Obstetrics and Gynecology, Maternal Fetal Medicine, San Antonio, Texas, USA
3 DO, LtCol, USA, Carl R. Darnall Military Medical Center, Chief of Obstetrics, Maternal Fetal Medicine, Killeen, Texas, USA
Address correspondence to:
Meghan Kathleen Munisteri
605 W Hollywood Ave, San Antonio, TX 78212,
USA
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Article ID: 100122Z08MM2022
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Munisteri MK, Gonzalez-Brown V, Villazana-Kretzer D. Amniotic band syndrome: A case series. J Case Rep Images Obstet Gynecol 2022;8(1):33–38.ABSTRACT
Introduction: Amniotic band sequence (ABS) is a constellation of congenital anomalies that can be seen in infants without any known genetic mutations. Amniotic band syndrome is thought to be responsible for 1/70 still births. There are two leading theories for proposed pathogenesis of ABS, commonly referred to as “extrinsic” and “intrinsic” models.
Case Series: Our case series depicts four deliveries at two large military hospitals. Each of our patient case demonstrates the spectrum of ABS and supports the extrinsic theory as the primary mechanism. The first case resulting in lateral encephalocele with a complex facial cleft and subsequent intrauterine fetal demise. The second patient case resulting in fetal unilateral lower extremity limb reduction. The third patient case resulting in premature prelabor rupture of membranes and delivery at 29 weeks with pedal amputation. The fourth and final patient case resulted in a lethal limb-body-wall defect with extravasation of visceral organs and a sacral myelomeningocele.
Conclusion: All four of our cases lend support to the extrinsic theory as the primary pathological mechanism. Each of our patients had risk factors for potential hypoxic injury and subsequent amniotic band formation.
Keywords: Amniotic band syndrome, Ectopic cordia, Fetal anomaly
SUPPORTING INFORMATION
Acknowledgments
We always grateful for the mentorship of Dr. Gonzalez-Brown and Dr. Villazana-Krezter.
Author ContributionsMeghan Kathleen Munisteri - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Veronica Gonzalez Brown - Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Diana Villazana-Kretzer - Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2022 Meghan Kathleen Munisteri et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
