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Case Report
Intravenous immunoglobulin therapy in the management of recurrent pregnancy loss: A case of successful pregnancy outcome in a woman with a history of 23 consecutive miscarriages
1 Maternal Fetal Medicine Fellow, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia
2 Resident in Obstetrics and Gynecology, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia
3 Consultant at the Department of Maternal Fetal Medicine, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia
Address correspondence to:
Wafa Alshahrani
Resident in Obstetrics and Gynecology, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh,
Saudi Arabia
Message to Corresponding Author
Article ID: 100234Z08HA2026
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How to cite this article
Alblewi H, Alshahrani W, Alsheikh M. Intravenous immunoglobulin therapy in the management of recurrent pregnancy loss: A case of successful pregnancy outcome in a woman with a history of 23 consecutive miscarriages. J Case Rep Images Obstet Gynecol 2026;12(2):1–4.ABSTRACT
Introduction: Recurrent pregnancy loss (RPL) is defined as two or three consecutive miscarriages and requires further investigations and management. Many causes such as genetic factors, immunological disturbances, anatomical abnormalities, and thrombophilia have been linked to cases of RPL. Multiple studies have investigated the outcomes of different treatment including Intravenous immunoglobulin (IVIG).
Case Report: We are presenting a case of woman with 23 consecutive pregnancy loss who was treated with IVIG during her pregnancy. The patient delivered at 34 weeks with no complications and discharged from the hospital in stable condition.
Conclusion: Further studies need to be conducted to establish the role of IVIG infusion in the treatment of patient with recurrent pregnancy loss.
Keywords: Consecutive abortions, Intravenous immunoglobulin, IVIG, IVIG with recurrent pregnancy loss, Management of recurrent pregnancy loss, Recurrent pregnancy loss
SUPPORTING INFORMATION
Author Contributions
Hedaya Alblewi - Substantial contributions to conception and design, Acquisition of data, Drafting the article, Final approval of the version to be published
Wafa Alshahrani - Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published
Mohammed Alsheikh - Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2026 Hedaya Alblewi et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
