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Case Report
Solitary fibrous tumor of liver: A case report
1 Master in Pathology, MD Pathologist, Assistant Pathologist, Laboratory of Pathological Anatomy, Lauro Wanderley University Hospital of the Federal University of Paraíba, João Pessoa, Paraíba, Brazil
2 Master in Health Sciences, MD Pathologist, Assistant Pathologist, Laboratory of Pathological Anatomy, Lauro Wanderley University Hospital of the Federal University of Paraíba, João Pessoa, Paraíba, Brazil
3 PhD in Health Sciences, MD Pathologist, Assistant Pathologist, Laboratory of Pathological Anatomy, Alcides Carneiro University Hospital of the Federal University of Campina Grande, Campina Grande, Pa, Brazil
4 Medicine Student, Faculty of Medical Sciences, João Pessoa, Paraíba, Brazil
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Ricella Maria Souza da Silva
Street Abelardo da Silva Guimarães Barreto, 115, Altiplano, João Pessoa, Paraíba 58046110,
Brazil
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Article ID: 101029Z01RS2019
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How to cite this article
Souza da Silva RM, Paz AR, Queiroga EM, Gouveia ÁRDS. Solitary fibrous tumor of liver: A case report. Int J Case Rep Images 2019;10:101029Z01RS2019.ABSTRACT
Introduction: Solitary fibrous tumors (SFTs) are a rare type of spindle cell neoplasm, composed of cellular and collagenous components, predominantly arise from the pleura. SFTs of the liver (SFTL) are uncommon with little number of cases reported in English literature. The diagnosis is based on histological and morphological characteristics, associated with immunohistochemical markers and molecular analysis. The rarity of this tumor makes it difficult to evaluate its prognosis and natural course. Surgical resection remains the mainstay of treatment. The present study reports a new case of SFTL and has the main purpose of updating the current knowledge.
Case Report: A 42-year-old woman presented with right hypochondrial discomfort and postprandial fullness. Magnetic nuclear resonance of the upper abdomen showing nodular expansive formation with well-defined contours and limits, located in left hepatic lobe. Insidious evolution, after three years of detection by imaging examination, submitted left hepatectomy. Macroscopically, a nodular mass, white color, firm and elastic, measuring 3.2×3.0 cm. Microscopic examination evidenced fusocellular proliferation, hypocellular and hypercellular areas (mild atypia), with predominance of a sclerotic pattern. The immunohistochemical study revealed ki-67 1%, positivity for STAT6, CD34 and Bcl-2. The diagnosis was of Solitary Fibrous Tumor Hepatic.
Conclusion: The SFTL is rare, with only 85 cases reported in the English Literature including the present case. The clinical presentation is habitually indolent. SFTL due to its rarity, its clinical presentation, study, treatment, and prognosis are not well known.
Keywords: Hepatic tumors, Liver, Solitary fibrous tumor, Soft tissue neoplasms
SUPPORTING INFORMATION
Acknowledgments
Thanks to Unit Pathology Laboratory of the University Hospital LauroWanderley and the pathologist Emílio Marcelo Pereira by the considerations and opinions about the case.
Author ContributionsRicella Maria Souza da Silva - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Alexandre Rolim da Paz - Acquisition of data, Analysis of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Eduardo Moreira de Queiroga - Acquisition of data, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Áfia Reginada Silva Gouveia - Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2019 Ricella Maria Souza da Silva et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
