Case Report


Amenorrhea in Russell-Silver syndrome calls for an early gynecological intervention

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1 St. Mary’s Medical Center, San Francisco, California, USA

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Taranika Sarkar

St. Mary’s Medical Center, San Francisco, California,

USA

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Article ID: 101035Z01TS2019

doi: 10.5348/101035Z01TS2019CR

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How to cite this article

Sarkar T, Allison C. Amenorrhea in Russell-Silver syndrome calls for an early gynecological intervention. Int J Case Rep Images 2019;10:101035Z01TS2019.

ABSTRACT


There has been considerable research on Russell-Silver Syndrome (RSS) which has an incidence of 1 in 30,000 to 1 in 100,000 people. Although numerous case reports have been published on children with RSS, very few have emphasized on adults. In this case report, we present a case of RSS in a 22-year-old women who presented with amenorrhea and abdominal pain. Normal menstrual cycle and normal estrogen level are necessary for bone health, lipid profile, cardiovascular health and mental health. An early intervention will thus help to reverse the effects of irregular menstrual cycles on long term health and address other causes like premature ovarian failure. The purpose of this report is to invite researchers to investigate whether there is a correlation between RSS and menstrual abnormalities, in which case early screening for ovarian and genital tract abnormalities in RSS will help to address the reproductive issues before a permanent consequence develops.

Keywords: Amenorrhea, Mayer-Rokitansky-Küster-Hauser, Russell-Silver syndrome

SUPPORTING INFORMATION


Acknowledgments

Dr. Abhishek Das, Prof. Dr. Jogenananda Pramanik and Dr. (Prof) Mohanchandra Mondal, JGD for their assistance with editing and formatting this paper.

Author Contributions

Taranika Sarkar - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Charles Allison - Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published

Source of Support

None

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2019 Taranika Sarkar et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.


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