Case Report


Pathological changes associated with DEFLUX use in vesicoureteric reflux

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1 Medical Intern, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates

2 Associate Professor, Pathology Department, College of Medicine & Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates

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Hajir Abdelrahman Abid

Medical Intern, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain,

United Arab Emirates

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Article ID: 101044Z01HA2019

doi: 10.5348/101044Z01HA2019CR

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How to cite this article

Abid HA, Almarzooqi S. Pathological changes associated with DEFLUX use in vesicoureteric reflux. Int J Case Rep Images 2019;10:101044Z01HA2019.

ABSTRACT


Vesicouretral reflux (VUR) which is the backflow of urine from the bladder to the kidneys leading to renal dysfunction. It is a common problem that is being encountered. Most of children and infants with UTI turn to be having VUR and patients who left untreated turned to have renal scarring and in turn to have end stage renal disease. For preventing these consequences, an intervention is needed. Previously, surgical intervention was the mainstay treatment and the new practice have endoscopic injection of deflux that is a gel-like material that consist of Dextranomer/Hyaluronic acid copolymer, which had replaced other methods of invasive antireflux surgeries and becoming the preferred method used in practice for solving VUR by building an artificial valve system. In the following case, we will highlight the histologic manifestation of the deflux injection.

Keywords: Deflux injection, Dextranomer microspheres, Vesicouretral reflux

SUPPORTING INFORMATION


Acknowledgments

Many thanks to Dr. Saeeda Almarzooqi for her patience and assistance in writing and proof reading of this case, assistance is appreciated and gratefully acknowledged.

Author Contributions

Hajir Abdelrahman Abid - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published

Saeeda Almarzooqi - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2019 Hajir Abdelrahman Abid et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.