Case Report


Fatal spontaneous intraperitoneal hemorrhage in association with apixaban: A case report

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1 MRCS, SHO, Department of Trauma and Orthopaedic Surgery, University Hospital Waterford, Dunmore Road, Waterford X91 ER8E, Ireland

2 FRCS, SpR, Department of Trauma and Orthopaedic Surgery, University Hospital Waterford, Dunmore Road, Waterford X91 ER8E, Ireland

3 FRCS, Consultant, Department of Trauma and Orthopaedic Surgery, University Hospital Waterford, Dunmore Road, Waterford X91 ER8E, Ireland

Address correspondence to:

Daniel P Mckenna

Department of Trauma and Orthopaedic Surgery, University Hospital Waterford, Dunmore Road, Waterford X91 ER8E,

Ireland

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Article ID: 101455Z01DM2024

doi: 10.5348/101455Z01DM2024CR

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How to cite this article

Mckenna DP, Kelly M, Murphy T. Fatal spontaneous intraperitoneal hemorrhage in association with apixaban: A case report. Int J Case Rep Images 2024;15(1):99–102.

ABSTRACT


We present the case of an 80-year-old gentleman with a spontaneous intraperitoneal hemorrhage secondary to direct oral anticoagulant (DOAC) medication. As far as we are aware this is the third documented case of spontaneous intraperitoneal hemorrhage in association with direct oral anticoagulants (DOACs) therapy. Previously published cases have also cited apixaban as the associated DOAC. With their increasing prevalence, spontaneous intraperitoneal hemorrhage should be a recognized presentation for the patient in extremis on DOAC therapy.

Keywords: Apixaban, Hemorrhage, Intraperitoneal, Spontaneous

SUPPORTING INFORMATION


Author Contributions

Daniel P Mckenna - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Final approval of the version to be published

Martin Kelly - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published

Terence Murphy - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2024 Daniel P Mckenna et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.


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