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Case Report
Primary pulmonary diffuse large B cell lymphoma presenting as a left lower lobe mass: A case report and literature review
1 Department of Internal Medicine, Northwell Health/Staten Island University Hospital, Staten Island, NY, USA
Address correspondence to:
Ghada Araji
MD, 475 Seaview Avenue, Staten Island, New York, NY 10305,
USA
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Article ID: 101463Z01GA2024
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How to cite this article
Araji G, Sajan S, Khamis Z, Al Achkar M, Khan S, Al Saidi I. Primary pulmonary diffuse large B cell lymphoma presenting as a left lower lobe mass: A case report and literature review. Int J Case Rep Images 2024;15(2):19–23.ABSTRACT
Introduction: Primary pulmonary diffuse large B cell lymphoma (PPDLBCL) is extremely rare neoplasm representing only 0.5–1% of primary pulmonary malignancies. Patients usually have non-specific clinical presentation and radiologic findings which makes it a challenging diagnosis.
Case Report: We report the case of an 82-year-old man presenting with cough and unintentional weight loss. Chest computed tomography (CT) showed an infra-hilar left lower lobe mass with a mediastinal subcarinal lymph node. Tissue sampling by endobronchial ultrasound (EBUS) resulted in the diagnosis of primary pulmonary diffuse large B cell lymphoma. He was started on R-CHOP chemotherapy regimen (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) and attained complete remission after 2 cycles.
Conclusion: The findings from this case indicate that primary pulmonary diffuse large B cell lymphoma should be considered in the differential diagnosis of primary pulmonary masses.
Keywords: Diffuse large B cell lymphoma, Lung mass, Non-Hodgkin lymphoma, Primary pulmonary lymphoma, R-CHOP chemotherapy
SUPPORTING INFORMATION
Author Contributions
Ghada Araji - Substantial contributions to conception and design, Acquisition of data, Revising it critically for important intellectual content, Final approval of the version to be published
Sah Sajan - Acquisition of data, Drafting the article, Final approval of the version to be published
Zaid Khamis - Acquisition of data, Drafting the article, Final approval of the version to be published
Michel Al Achkar - Acquisition of data, Drafting the article, Final approval of the version to be published
Salman Khan - Acquisition of data, Drafting the article, Final approval of the version to be published
Ibrahim Al Saidi - Acquisition of data, Drafting the article, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2024 Ghada Araji et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
