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Case Series
A case series of intertriginous rashes in cancer patients
1 Researcher, University of South Florida, Tampa, FL, USA
2 Student Researcher, Dermatology and Cutaneous Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA
3 Professor, Infectious Diseases and Tropical Medicine, Moffitt Cancer Center & Research Institute, Tampa, FL, USA
Address correspondence to:
Alexandria Weygand
31027 Edendale Drive, Wesley Chapel, FL 33543,
USA
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Article ID: 101472Z01AW2024
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How to cite this article
Weygand A, Patra P, Greene J. A case series of intertriginous rashes in cancer patients. Int J Case Rep Images 2024;15(2):62–68.ABSTRACT
Introduction: Immunocompromised patients, especially those with cancer, face an elevated risk of developing inflamed and painful rashes between the skinfolds. These intertriginous conditions are not always easy to identify.
Case Series: We report a case series of three neutropenic patients, two with acute myeloblastic leukemia (AML) and one with metastatic left invasive ductal carcinoma, presenting to the hospital dermatology consult team with intertriginous skin eruptions. The patients were diagnosed with symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), ecthyma gangrenosum, and toxic erythema of chemotherapy. Treatment and management of these cases involved topical steroids, antibiotics, and chemotherapy dosing adjustment.
Conclusion: This paper explores the various infectious, inflammatory, and other etiologies of intertriginous rashes in immunocompromised and neutropenic patients.
Keywords: Acute myeloblastic leukemia, Intertrigo, Neutropenia, SDRIFE
SUPPORTING INFORMATION
Author Contributions
Alexandria Weygand - Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Pratiksha Patra - Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
John Greene - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2024 Alexandria Weygand et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
