Case Report


Uncommon cause of lymphocytosis: Case report of lymphocytosis secondary to lithium usage

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1 Internal Medicine Specialist, Internal Medicine, Hacettepe University, Ankara, Turkey

2 Hematology Fellowship Trainee, Hematology Department, Hacettepe University, Ankara, Turkey

3 Associate Professor of Hematology, Hematology Department, Hacettepe University, Ankara, Turkey

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Deniz Donmez

Yukari Dikmen Mahallesi 639, Cadde 11/7 Kervan Apt., Cankaya/Ankara,

Turkey

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Article ID: 101473Z01DD2024

doi: 10.5348/101473Z01DD2024CR

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How to cite this article

Donmez D, Ilgaz M, Malkan ÜY. Uncommon cause of lymphocytosis: Case report of lymphocytosis secondary to lithium usage. Int J Case Rep Images 2024;15(2):69–72.

ABSTRACT


Lithium, which is widely used in mood disorders, has several side effects. Lymphocytosis is a rare side effect. The patient was a young man in his twenties. The patient referred from psychiatry for persistent lymphocytosis. After the initial evaluation, the possible relationship between lithium and lymphocyte levels was considered. The diagnosis of lymphocytosis secondary to lithium intake can only be made with the elimination of other possible causes of lymphocytosis. Therefore, possible viral infections, possible drug interactions, possible systemic diseases, and malignancies were evaluated and eliminated. After evaluation, a correlation was found between lithium blood level and lymphocyte count. The patient started to be followed up.

Keywords: Leukemia, Leukocytosis, Lithium, Lymphocytosis

SUPPORTING INFORMATION


Author Contributions

Deniz Donmez - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Meral Ilgaz - Substantial contributions to conception and design, Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published

Ümit Yavuz Malkan - Substantial contributions to conception and design, Analysis of data, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2024 Deniz Donmez et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.