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Case Report
Dapsone-induced Methemoglobinemia in a patient with history of Lichen Planus: A case report
1 Department of General Medicine, GMERS Medical College and Hospital, Sola, Ahmedabad, Gujarat, India
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Nandini Kaushik Dave
Department of General Medicine, GMERS Medical College and Hospital, Sola, Ahmedabad, Gujarat,
India
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Article ID: 101497Z01ND2025
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Dave NK. Dapsone-induced methemoglobinemia in a patient with history of lichen planus: A case report. Int J Case Rep Images 2025;16(1):43–47.ABSTRACT
This is a case of a 51-year-old patient with a history of lichen planus on dapsone having methemoglobinemia, with G6PD blood levels that are on the lower range. The primary focus of the case report is on the mechanism of dapsone-induced methemoglobinemia along with a discussion over methemoglobinemia, its signs and symptoms, diagnosis, and the line of treatment for the same. Methemoglobinemia could be fatal if left undiagnosed and not treated on time.
Keywords: Dapsone, G6PD enzyme, Half life, Methemoglobinemia, Methylene blue, Nikolsky sign, Vitamin C
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Author Contributions
Nandini Kaushik Dave - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthor declares no conflict of interest.
Copyright© 2025 Nandini Kaushik Dave. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
