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Case Series
Stable lung function with pulmonary Langerhans cell histiocytosis in pregnancy
1 Department of Obstetrics & Gynecology, Christiana Care Health System, Newark, DE, USA
2 Division of Maternal Fetal Medicine, Christiana Care Health System, Newark, DE, USA
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Ghamar Bitar
Department of Obstetrics & Gynecology, 4755 Ogletown-Stanton Road, Newark, DE 19718,
USA
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Article ID: 100063Z08GB2020
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Bitar G, Shlossman P. Stable lung function with pulmonary Langerhans cell histiocytosis in pregnancy. J Case Rep Images Obstet Gynecol 2020;6: 100063Z08GB2020.ABSTRACT
Introduction: Few studies have evaluated the effect of pulmonary Langerhans cell histiocytosis on lung function in pregnancy and the appropriate mode of delivery.
Case Series: Case 1 details a young multiparous female affected by pulmonary Langerhans cell histiocytosis with the need for baseline oxygen therapy outside of pregnancy and fetus with severe growth restriction requiring delivery at term by cesarean section. Case 2 includes a young multiparous female with pulmonary Langerhans cell histiocytosis with an uncomplicated pregnancy course and delivery at term by cesarean section.
Conclusion: In patients with pulmonary Langerhans cell histiocytosis, lung function typically remains stable in pregnancy. Interstitial lung disease may affect birth weight. There may be a recommendation for delivery by cesarean section to reduce pneumothorax risk.
Keywords: Cesarean section, High risk pregnancy, Langerhans cell histiocytosis, Low birth weight infant
SUPPORTING INFORMATION
Author Contributions
Ghamar Bitar - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Philip Shlossman - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2020 Ghamar Bitar et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
