Case Report


Primary amenorrhea due to sclerotic or “non-functional” endometrium: Case presentation and literature review

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1 Specialist Obstetrician & Gynaecologist, Department of Obstetrics and Gynaecology, Royal Darwin Hospital, Australia

2 Registrar in Obstetrics & Gynaecology, Department of Obstetrics and Gynaecology, Royal Darwin Hospital, Australia

Address correspondence to:

Nader Gad

PO BOX 41326, Casuarina, NT 0811,

Australia

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Article ID: 100064Z08NG2020

doi: 10.5348/100064Z08NG2020CR

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How to cite this article

Gad N, Yam C, Thomas S. Primary amenorrhea due to sclerotic or “non-functional” endometrium: Case presentation and literature review. J Case Rep Images Obstet Gynecol 2020;6: 100064Z08NG2020.

ABSTRACT


Primary amenorrhea is less common than secondary amenorrhea. It can be caused by various anatomical, genetic, or hormonal factors during the development of the reproductive organs. Congenital absence of the endometrium or sclerotic endometrium is a very rare cause of primary amenorrhea with only three cases previously reported in English literature. We describe a case of sclerotic or non-functional endometrium in the context of Mullerian abnormality and normal female karyotype 46 XX.

Keywords: Absent endometrium, Non-functional endometrium, Primary amenorrhea, Sclerotic endometrium

SUPPORTING INFORMATION


Author Contributions

Nader Gad - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Chantelle Yam - Substantial contributions to conception and design, Acquisition of data, Interpretation of data, Drafting the article, Final approval of the version to be published

Sujatha Thomas - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published

Guaranter of Submission

The corresponding author is the guarantor of submission.

Source of Support

None

Consent Statement

Written informed consent was obtained from the patient for publication of this article.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Conflict of Interest

Authors declare no conflict of interest.

Copyright

© 2020 Nader Gad et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.