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Case Report
Cellular angiofibroma: A rare labia minor tumor
1 Department of Obstetrics and Gynecology, Centro Hospitalar de Entre Douro e Vouga, Santa Maria da Feira, Portugal
2 Anatomical Pathology Department, Unilabs, Centro Hospitalar de Entre Douro e Vouga, Santa Maria da Feira, Portugal
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Patrícia Gomes Ferreira
Department of Obstetrics and Gynecology, Centro Hospitalar de Entre Douro e Vouga, Santa Maria da Feira,
Portugal
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Article ID: 100155Z08PF2023
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How to cite this article
Ferreira PG, Carneiro C, Saraiva S, Ferreira V, Scigliano H, Monteiro I. Cellular angiofibroma: A rare labia minor tumor. J Case Rep Images Obstet Gynecol 2023;9(2):7–11.ABSTRACT
Cellular angiofibroma of the vulva is a rare benign mesenchymal tumor in middle-aged women, first reported in 1997 by Nucci et al. It is important to differentiate cellular angiofibroma from other tumors as these may be more aggressive and recurring. Cellular angiofibroma has a limited potential for local recurrence and is usually treated with complete local excision. A 45-year-old woman was referred to the gynecology appointment with a complaint of a discomfort mass in the right labium minus 1 year before, which has been progressively increasing in size for the past three months up to 6 cm. No change in vulvar skin color, local itching, or bilateral inguinal adenopathy. The tumor was excised, and the histopathological exam revealed a cellular angiofibroma. The patient recovered well and a good aesthetic result was achieved. This is the first case described of the cellular angiofibroma which arises from one of the labia minora. It is bigger in size and growing more rapidly than usual within three months. A simple excision was carried out and until now (12 months after) no recurrence signals.
Keywords: Cellular angiofibroma, Histopathology, Immunohistochemistry, Mesenchymal tumors, Vulva
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Author Contributions
Patrícia Gomes Ferreira - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Carolina Carneiro - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Susana Saraiva - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Vânia Ferreira - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Horácio Scigliano - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Isabel Monteiro - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Patrícia Gomes Ferreira et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
