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Case Report
Complete molar pregnancy: A case report
1 Resident Physician, Obstetrics and Gynecology, SUNY Downstate Health Sciences University, Brooklyn, NY, United States of America
2 Urogynecology fellow, Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, MO, United States of America
3 Attending physician, Obstetrics and Gynecology, Kings County Health and Hospital Center, Brooklyn, NY, United States of America
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Ranjitha Vasa
450 Clarkson Avenue, Brooklyn, NY 11203,
United States of America
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Article ID: 100201Z08RV2025
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Vasa R, Thompson M, Soyemi SA, Gosine V. Complete molar pregnancy: A case report. J Case Rep Images Obstet Gynecol 2025;11(1):64–68.ABSTRACT
Introduction: Complete hydatidiform mole, a form of gestational trophoblastic disease, occurs when one sperm fertilizes an empty ovum. Complete trophoblastic proliferation is associated with elevated serum beta human chorionic gonadotropin levels and absence of a fetus. Classic clinical features include abnormal vaginal bleeding, hyperemesis, and enlarged uterus for gestational age. Less common features include hyperthyroidism, early onset pre-eclampsia, and bilateral ovarian thecalutein cysts.
Case Report: We present a case of a complete molar pregnancy of a woman who presented to the emergency department at 18 and 4/7 weeks with complaints of irregular vaginal spotting. Serum beta human chorionic gonadotropin level was noted to be 59,401. Transvaginal ultrasound notable for absence of intrauterine gestation with complex heterogeneous material within the uterus. The patient underwent suction dilatation and curettage. Histological examination of curettings confirmed a complete hydatidiform mole. The patient with persistently elevated blood pressures post-operatively necessitated workup for pre-eclampsia, which was negative. Given elevated blood pressures, the patient was started on Labetalol 200 mg twice daily with improvement one month post-procedure. Today, she no longer requires anti-hypertensive medication and beta human chorionic gonadotropin level has appropriately down trended.
Conclusion: Our case highlights the need for early imaging to detect abnormalities like hydatidiform moles, which pose significant risks. Early detection improves patient outcomes and ensures proper post-operative care.
Keywords: Case report, Hydatidiform mole, Molar pregnancy, Obstetrics, Pregnancy
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Author Contributions
Ranjitha Vasa - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Marae Thompson - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sarin Abiola Soyemi - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Valini Gosine - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2025 Ranjitha Vasa et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
