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Case Report
Retroperitoneal schwannoma: An abnormal presentation mimicking a pelvic mass
1 Department of Obstetrics and Gynecology, Medical City Arlington, 3301 Matlock Road, Arlington, TX, USA
2 Texas College of Osteopathic Medicine, 3500 Camp Bowie Boulevard, Fort Worth, TX, USA
Address correspondence to:
Isabella Sciacca
3201 Matlock Road, Suite 220, Arlington, TX 76015,
USA
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Article ID: 100212Z08IS2025
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Sciacca I, Reeves C, Stokes C, Seligman S. Retroperitoneal schwannoma: An abnormal presentation mimicking a pelvic mass. J Case Rep Images Obstet Gynecol 2025;11(2):18–22.ABSTRACT
Introduction: A schwannoma is an encapsulated nerve sheath tumor originating from differentiated Schwann cells. Schwannomas are preferentially localized to the head, neck, and extremities with a minor occurrence of 1–3% in the retroperitoneal space. Schwannomas are often asymptomatic due to slow growth but can be present with symptoms according to their location. We report a case of a 45-year-old female with a retroperitoneal schwannoma that initially was suspected to be an ovarian mass.
Case Report: A 45-year-old female with a 10-year history of a right ovarian cyst presented with lower abdominal pain, early satiety, hematuria, low back pain and constipation. Transabdominal ultrasound showed right ovarian enlargement measuring 8.8 × 6.6 cm, described as heterogeneous with loculations. Tumor markers indicated a low risk of malignancy. The patient was taken to the operating room for an exploratory laparotomy that revealed a large, firm posterior pelvic mass palpated in the retroperitoneal space. The cyst wall could not be completely dissected due to proximity to major vessels and nerve roots. The patient was referred to a neighboring academic institution because of the case complexity. She underwent repeat exploratory laparotomy and neuroplasty of the L5, S1, and S2 nerve roots. The L5 nerve root was ultimately sacrificed and the retroperitoneal mass was removed. Final pathology revealed a benign schwannoma.
Conclusion: The diagnosis of a retroperitoneal schwannoma is often missed because of its rare occurrence, location, vague symptoms, and resemblance to other tumors on varying imaging modalities. Due to low incidence and often delay in diagnosis, current management guidelines are limited. Currently, histopathological exam after total surgical resection is the most reliable source for diagnosis. The patient in this case demonstrates the need for improvement in the preoperative evaluation and consideration of non-gynecologic differential diagnoses in the evaluation of a suspected pelvic mass.
Keywords: Case report, Misdiagnosis, Ovarian mass, Pelvic mass, Retroperitoneal schwannoma, Retroperitoneum, Schwannoma
SUPPORTING INFORMATION
Acknowledgments
We thank the Medical City Arlington Department of Pathology for assistance in obtaining and permission of use of the images in this manuscript.
Author ContributionsIsabella Sciacca - Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Christelle Reeves - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Cameron Stokes - Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Steven Seligman - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2025 Isabella Sciacca et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
