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Case Report
Large uterine leiomyoma presenting as pseudo-Meigs’ syndrome with an elevated CA 125: Case report and literature review
1 Student, School of Medicine, The University of Texas Medical Branch, Galveston, Texas, United States
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Jake Alan Gibbons
500 Seawall Blvd Unit 1109, Galveston, Texas 77550,
United States
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Article ID: 100046Z08JG2019
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Gibbons JA. Large uterine leiomyoma presenting as pseudo-Meigs’ syndrome with an elevated CA 125: Case report and literature review. J Case Rep Images Obstet Gynecol 2019;5:100046Z08JG2019.ABSTRACT
Introduction: Uterine leiomyomas presenting as pseudo-Meigs’ syndrome with an elevated CA 125 are rare and pose a diagnostic challenge for physicians.
Case Report: A 35-year-old G0P0 presented to the emergency department with a chief complaint of abdominal swelling and weight gain beginning one month ago. Laboratory work was significant for an elevated CA 125. She was found to have a large mass originating from her uterus. Following resection of the mass, her symptoms resolved. Pathology of the mass came back as a uterine leiomyoma.
Conclusion: Generally, findings of ascites, a pelvic mass, and an elevated CA 125 in a female suggests a diagnosis of ovarian cancer. However, as demonstrated by our case and others, benign causes such as Meigs’ syndrome and pseudo-Meigs’ syndrome should also be considered. Surgery is the mainstay of treatment in pseudo-Meigs’ syndrome. Resolution of the ascites and hydrothorax occurs spontaneously following resection of the tumor.
Keywords: Ascites, CA 125, Gynecology, Leiomyoma, Pseudo-Meigs’ syndrome
SUPPORTING INFORMATION
Author Contributions
Jake Alan Gibbons - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionMeigs JV. Fibroma of the ovary with ascites and hydrothorax; Meigs’ syndrome. Am J Obstet Gynecol 1954;67(5):962–85.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2019 Jake Alan Gibbons. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
